Publication: Laser ablation-assisted synthesis of plasmonic si@au core-satellite nanocomposites for biomedical applications
Дата
2021
Авторы
Al-Kattan, A.
Tselikov, G.
Metwally, K.
Mensah, S.
Popov, A. A.
Kabashin, A. V.
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© 2021 by the authors. Licensee MDPI, Basel, Switzerland.Owing to strong plasmonic absorption and excellent biocompatibility, gold nanostruc-tures are among best candidates for photoacoustic bioimaging and photothermal therapy, but such applications require ultrapure Au-based nanoformulations of complex geometry (core-shells, nano-rods) in order to shift the absorption band toward the region of relative tissue transparency (650– 1000 nm). Here, we present a methodology for the fabrication of Si@Au core-satellite nanostruc-tures, comprising of a Si core covered with small Au nanoparticles (NP), based on laser ablative synthesis of Si and Au NPs in water/ethanol solutions, followed by a chemical modification of the Si NPs by 3-aminopropyltrimethoxysilane (APTMS) and their subsequent decoration by the Au NPs. We show that the formed core-satellites have a red-shifted plasmonic absorption feature compared to that of pure Au NPs (520 nm), with the position of the peak depending on APTMS amount, water−ethanol solvent percentage and Si−Au volume ratio. As an example, even relatively small 40-nm core-satellites (34 nm Si core + 4 nm Au shell) provided a much red shifted peak centered around 610 nm and having a large tail over 700 nm. The generation of the plasmonic peak is confirmed by modeling of Si@Au core-shells of relevant parameters via Mie theory. Being relatively small and exempt of any toxic impurity due to ultraclean laser synthesis, the Si@Au core-satellites promise a major advancement of imaging and phototherapy modalities based on plasmonic properties of na-nomaterials.
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Laser ablation-assisted synthesis of plasmonic si@au core-satellite nanocomposites for biomedical applications / Al-Kattan, A. [et al.] // Nanomaterials. - 2021. - 11. - № 3. - P. 1-13. - 10.3390/nano11030592