Publication: Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions
Дата
2019
Авторы
Journal Title
Journal ISSN
Volume Title
Издатель
Аннотация
Copyright © 2019 SPIE.Methods of femtosecond laser ablation in deionized water were used to fabricate ultrasmall (< 2 nm), bare (ligand-free) organic luminophore DCEtDCS nanoparticles, which exhibit aggregation enhanced emission in the green range (533 nm) with the quantum yield exceeding 58% and provide no concentration quenching. In contrast to chemically synthesized counterparts, laser-synthesized DCEtDCS nanoparticles do not contain any organic impurities due to their preparation in aqueous medium and do not require surfactants to stabilize colloidal solutions, which makes them highly suitable for intracellular uptake and bioimaging. The highly negative surface charge of these nanoparticles impeded their cellular uptake, but when the surface was coated with chitosan, a cationic polymer, intracellular uptake in microglia was achieved. Using in vitro model, we finally demonstrate the efficient employment of ultrasmall and surfactant free fluorescent organic nanoparticles prepared by laser ablation as markers in bioimaging.
Описание
Ключевые слова
Цитирование
Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions / Lim, C.-K. [et al.] // Proceedings of SPIE - The International Society for Optical Engineering. - 2019. - 10907. - 10.1117/12.2513821
URI
https://www.doi.org/10.1117/12.2513821
https://www.scopus.com/record/display.uri?eid=2-s2.0-85066811820&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000474768700008
https://openrepository.mephi.ru/handle/123456789/18227
https://www.scopus.com/record/display.uri?eid=2-s2.0-85066811820&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000474768700008
https://openrepository.mephi.ru/handle/123456789/18227