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Laser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions

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dc.contributor.authorLim, C. -K.
dc.contributor.authorPopov, A. A.
dc.contributor.authorTselikov, G.
dc.contributor.authorHeo, J.
dc.contributor.authorKabashin, A. V.
dc.contributor.authorPrasad, P. N.
dc.contributor.authorКабашин, Андрей Викторович
dc.date.accessioned2024-11-21T09:27:22Z
dc.date.available2024-11-21T09:27:22Z
dc.date.issued2019
dc.description.abstractCopyright © 2019 SPIE.Methods of femtosecond laser ablation in deionized water were used to fabricate ultrasmall (< 2 nm), bare (ligand-free) organic luminophore DCEtDCS nanoparticles, which exhibit aggregation enhanced emission in the green range (533 nm) with the quantum yield exceeding 58% and provide no concentration quenching. In contrast to chemically synthesized counterparts, laser-synthesized DCEtDCS nanoparticles do not contain any organic impurities due to their preparation in aqueous medium and do not require surfactants to stabilize colloidal solutions, which makes them highly suitable for intracellular uptake and bioimaging. The highly negative surface charge of these nanoparticles impeded their cellular uptake, but when the surface was coated with chitosan, a cationic polymer, intracellular uptake in microglia was achieved. Using in vitro model, we finally demonstrate the efficient employment of ultrasmall and surfactant free fluorescent organic nanoparticles prepared by laser ablation as markers in bioimaging.
dc.identifier.citationLaser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions / Lim, C.-K. [et al.] // Proceedings of SPIE - The International Society for Optical Engineering. - 2019. - 10907. - 10.1117/12.2513821
dc.identifier.doi10.1117/12.2513821
dc.identifier.urihttps://www.doi.org/10.1117/12.2513821
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85066811820&origin=resultslist
dc.identifier.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000474768700008
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/18227
dc.relation.ispartofProceedings of SPIE - The International Society for Optical Engineering
dc.titleLaser-ablative synthesis of aggregation-induced enhanced emission luminophore dyes in aqueous solutions
dc.typeConference Paper
dspace.entity.typePublication
oaire.citation.volume10907
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