Publication: Evaluating the dynamics of brain tissue oxygenation using near-infrared spectroscopy on various experimental models
Дата
2019
Авторы
Kustov, D. M.
Sharova, A. S.
Makarov, V. I.
Borodkin, A. V.
Savelieva, T. A.
Loschenov, V. B.
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Аннотация
© 2019 Astro Ltd.In this paper we consider a method for researching the dynamics of blood flow in the cerebral cortex, on an optical phantom that reproduces the parameters of real human and mice brain structures, through the use of near and infrared ranges of laser radiation. For the investigation of real tissue we chose a laboratory mouse brain in vivo. An algorithm for non-invasive diagnostics of the degree of oxygenation was identified and optimal parameters of installation components were selected for taking information about hemodynamic indicators. Output was verified by the reference method for assessing oxygenation by degree of absorption of hemoglobin in the visible range, which indicates that data have a high correlation with classical methods. With further development, this algorithm can be used in various areas of research and diagnostics.
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Цитирование
Evaluating the dynamics of brain tissue oxygenation using near-infrared spectroscopy on various experimental models / Kustov, D.M. [et al.] // Laser Physics Letters. - 2019. - 16. - № 11. - 10.1088/1612-202X/ab4182
URI
https://www.doi.org/10.1088/1612-202X/ab4182
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https://openrepository.mephi.ru/handle/123456789/19012
https://www.scopus.com/record/display.uri?eid=2-s2.0-85076284153&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000503759300002
https://openrepository.mephi.ru/handle/123456789/19012