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Гончуков, Сергей Александрович

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Институт лазерных и плазменных технологий
Стратегическая цель Института ЛаПлаз – стать ведущей научной школой и ядром развития инноваций по лазерным, плазменным, радиационным и ускорительным технологиям, с уникальными образовательными программами, востребованными на российском и мировом рынке образовательных услуг.
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Гончуков
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Сергей Александрович
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  • Публикация
    Только метаданные
    Electroactive nanostructured antibacterial materials
    (2022) Saraeva, I. N.; Zayarny, D. A.; Tolordava, E. R.; Nastulyavichus, A. A.; Gonchukov, S. A.; Гончуков, Сергей Александрович
    © 2022 Astro Ltd.Thin nanostructured metal (Au, Ag) films, magnetron-sputtered on semiconductor (n-type Si) substrate under 6 V voltage exposure for 15 min, exhibit high antibacterial effect against the food pathogens S. aureus and P. aeruginosa. Nanostructures were formed by femtosecond laser ablation, resulting in an array of microspots. The observed effect is caused by the emergence of submicron, laterally periodical static electric and magnetic fields, adjacent to the metal film, causing the abrupt voltage drops, which induce the hyperpolarization of the cell membrane and increase its permeability, resulting in the formation of pores (electroporation) in the membrane and the subsequent apoptosis of the bacterial cell. Additional factors, which enhance the antibacterial effect of the studied materials, are the volume convection in the liquid drop with bacterial culture, caused by the moderate heating of the substrate to 45 °C-50 °C during the electric current flow and electro-taxis of bacteria to the charged nanostructured metal film.
  • Публикация
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    Directional autonomous water flow in laser-engineered microfluidic gradient structures on polymethylmetacrylate-coated steel surface
    (2020) Krylach, I. V.; Kudryashov, S. I.; Fokina, M. I.; Sitnikova, V. E.; Gonchukov, S. A.; Гончуков, Сергей Александрович
    © 2020 Astro Ltd.Autonomous directional water flow was demonstrated on a laser-microstructured steel-supported polymethylmetacrylate (PMMA) film with a surface tension gradient. For this purpose, a 4 μm-thick PMMA layer on AISI 304 steel surface was raster-scanned in air in ablative mode by a 1064 nm, 100 ns laser beam in a number of lines, with the amount and topography of ablated PMMA analyzed by optical microscopy, profilometry and IR spectroscopy. Such scanning, performed at increasing incident fluences, produced a series of chemically and topographically modified, differently water-wet neighbouring mm-sized spots, autonomously driving single-droplet water flow along the surface tension (contact angle) gradient.
  • Публикация
    Только метаданные
    A bacterial misericorde: laser-generated silicon nanorazors with embedded biotoxic nanoparticles combat the formation of durable biofilms
    (2020) Saraeva, I. N.; Tolordava, E. R.; Nastulyavichus, A. A.; Ivanova, A. K.; Kudryashov, S. I.; Gonchukov, S. A.; Гончуков, Сергей Александрович
    A combined mechano- and chemo-bactericidal nanomorphology, consisting of periodical surface structures on silicon with deposited nanoparticles of selenium, tellurium oxide, antimony oxide and silver, was fabricated via laser ablation in deionized water with femto- and nanosecond laser systems. The resulting functional surfaces were tested against the formation of Staphylococcus aureus biofilms, and their morphology and elemental composition was characterized with scanning electron microscopy and energy-dispersive x-ray and Raman spectroscopy. Antibacterial properties were suggested to originate from the combined chemical toxicity of nanoparticles and the mechanical damage caused by the sharp nanoscale relief on silicon.
  • Публикация
    Только метаданные
    Direct laser writing regimes for bulk inscription of polarization-based spectral microfilters and fabrication of microfluidic bio/chemosensor in bulk fused silica
    (2022) Kudryashov, S. I.; Danilov, P. A.; Rupasov, A. E.; Smayev, M. P.; Gonchukov, S. A.; Гончуков, Сергей Александрович
    © 2022 Astro LtdLaser inscription of form-birefringent nanograting layers inside fused silica by ultrashort (femto-picosecond) laser pulses at 515 nm was studied as a function of laser, average power and pulsewidth in terms of fabrication regimes. Retardance magnitudes were acquired for single birefringent layers inscribed at different laser parameters, enabling fabrication of polarization-based spectral micro-filters in the form of few-layer microdevices and of microfluidic multi-color refractive-index chemo/biosensor.
  • Публикация
    Только метаданные
    Focusing effects during ultrashort-pulse laser ablative generation of colloidal nanoparticles for antibacterial applications
    (2022) Nastulyavichus, A.; Kudryashov, S.; Ionin, A.; Yushina, Y.; Gonchukov, S.; Гончуков, Сергей Александрович
    Ultrashort (femto-picosecond) laser pulses with supercritical peak pulse powers undergo self-focusing and multiple filamentation during their propagation in transparent media. In this work, a comparative study of propagation and position-dependent ablation of a gold target in water by 0.3 ps and 10 ps 1030 nm laser pulses was performed. The filamentary laser propagation was visualized in water by the corresponding pre-focal plasma channels. The position-dependent ablative optical density yield of colloidal solutions and target mass loss along the filamentary tracks in water were characterized, for the first time enabling straightforward enhancement of colloidal generation for anti-bacterial, biomedical and nanophotonics applications. © 2022 Astro Ltd.
  • Публикация
    Только метаданные
    Laser bioprinting without donor plate
    (2022) Cheptsov, V.; Minaev, N.; Zhigarkov, V.; Tsypina, S.; Gonchukov, S.; Гончуков, Сергей Александрович
    © 2022 Astro Ltd.A promising laser bioprinting technology based on the effect of laser-induced direct transfer is rapidly developing and is already actively used in biotechnology and medicine today. Typically, such technologies use donor plates with an absorbent coating, from which gel microdroplets with living cells and microorganisms are transferred to an acceptor substrate under the action of a laser pulse. This article proposes a new bioprinting technology that makes it possible to transfer microdroplet not only without an absorbing coating, but also without the donor plate itself. The essence of this method is that the transfer to the surface of the acceptor is carried out by a series of nanosecond pulse with a wavelength of 3 μm directly from the surface of a liquid with microorganisms. The mechanism of a liquid jet and microdroplets formation upon absorption of a laser pulse in a thin surface liquid layer is discussed in detail. It has been shown that microorganisms transferred using the new bioprinting technology are viable and can be successfully cultivated on a dense nutrient medium.
  • Публикация
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    The optical refractometry using transport-of-intensity equation
    (2022) Gritsenko, I. V.; Kovalev, M. S.; Stsepuro, N. G.; Gulina, Y. S.; Gonchukov, S. A.; Гончуков, Сергей Александрович
    © 2022 Astro Ltd.A development of a method for measuring the refractive index of optical media based on the transport-of-intensity equation (TIE) is proposed. The method requires only a complementary metal-oxide semiconductor (CMOS) camera, which registers intensity distributions in several planes. The obtained intensity distributions are used to solve the TIE, known as a non-interferometric and deterministic method of measuring the phase of a light wave. Simple physical relations connecting the phase of the light wave that has passed through an optical medium and its refractive index allows to determine the latter. The results of the experiment confirm the applicability of the proposed method to the problems of optical refractometry.
  • Публикация
    Открытый доступ
    Внутрирезонаторная отражательная лазерная фазометрия
    (1987) Баранков, В. В.; Гольтяев, О. М.; Гончуков, С. А.; Гончуков, Сергей Александрович
  • Публикация
    Только метаданные
    Fabrication of micro-optical connectors for electro-optical sensor devices by a combined femtosecond laser system
    (2021) Epifanov, E. O.; Tarkhov, M. A.; Timofeeva, E. R.; Trofimov, I. V.; Gonchukov, S. A.; Гончуков, Сергей Александрович
    © 2021 Astro Ltd.The article demonstrates the fundamental possibility of creating microstructures for various functional purposes using the capabilities of the two-photon femtosecond polymerization method. The developed technological approach for creating a micro-optical holder for standard single-mode and multimode fibers is demonstrated. This type of holder can be used to manufacture a unit for optical matching of optical fibers with sensitive optical elements. The possibility of optical matching of fibers with a superconducting single-photon detector, an array system of bolometric superconducting microbridges, and spherical self-formed microlenses by near infrared-sensitive photopolymerization has been experimentally shown. The device manufacturing process was carried out in a combined single laser micromachining facility using femtosecond laser radiation for lithography with submicron resolution, texturing of the sensor surface, and the formation of microstructures for installing single-mode optical fibers.
  • Публикация
    Только метаданные
    You shall not pass: Ti nanospike-based sterilizer in fluid flow reactor
    (2021) Saraeva, I. N.; Tolordava, E. R.; Sozaev, I. V.; Nastulyavichus, A. A.; Gonchukov, S. A.; Гончуков, Сергей Александрович
    We report the laser-ablative fabrication of antibacterial nanostructures, combining mechanical and chemotoxic effects, by femto- and nanosecond laser ablation and their testing on Staphylococcus aureus and Pseudomonas aeruginosa strains. A Ti surface, covered with nanospikes and periodical surface ripples, provides a strong anti-biofilm effect, and the addition of cytotoxic nanoparticles (NPs) (Ag, Se) enhances the overall bactericidal activities. A flow reactor, including Ti nanospike-covered wafers as a through-flow sterilizer, allowed reduction of the bacterial population by two orders. Several types of nanostructures with/without biofilms were characterized by scanning electron microscopy and energy-dispersive x-ray spectroscopy. Their antibacterial properties were demonstrated by standard live/dead tests and were suggested to originate from the combined chemical toxicity of NPs and mechanical damage caused by sharp nanoscale relief on Ti.