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Radiation-induced transgenerational effects in animals

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dc.contributor.authorDubrova, Y. E.
dc.contributor.authorSarapultseva, E. I.
dc.contributor.authorСарапульцева, Елена Игоревна
dc.date.accessioned2024-12-26T06:53:20Z
dc.date.available2024-12-26T06:53:20Z
dc.date.issued2022
dc.description.abstract© Copyright © 2020 Taylor and Francis Group LLC.According to the results of recent studies, parental exposure to ionizing radiation not only leads to mutation induction in the germline of irradiated animals but also affects their non-exposed offspring. These radiation-induced transgenerational effects belong to an epigenetic phenomenon that could not be defined as a transmission of altered phenotypes from the irradiated parents to their non-exposed offspring. In this review, we present the results of laboratory studies aimed to evaluate the transgenerational effects of parental irradiation on a number of traits in the offspring of exposed parents. The results of animal studies showing compromised viability, fertility and genome stability among the non-exposed offspring of irradiated parents are presented and discussed. So far, the epigenetic phenomenon of radiation-induced transgenerational effects has been established in laboratory studies. Future work should address the important issue of manifestation of radiation-induced transgenerational effects in populations inhabiting radioactive-contaminated areas, as well as the mechanisms of transgenerational effects.
dc.identifier.citationDubrova, Y. E. Radiation-induced transgenerational effects in animals / Dubrova, Y.E., Sarapultseva, E.I. // International Journal of Radiation Biology. - 2022. - 10.1080/09553002.2020.1793027
dc.identifier.doi10.1080/09553002.2020.1793027
dc.identifier.urihttps://www.doi.org/10.1080/09553002.2020.1793027
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85088995338&origin=resultslist
dc.identifier.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000555261200001
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/28555
dc.relation.ispartofInternational Journal of Radiation Biology
dc.titleRadiation-induced transgenerational effects in animals
dc.typeReview
dspace.entity.typePublication
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