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Properties and Printability of the Synthesized Hydrogel Based on GelMA

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dc.contributor.authorArguchinskaya, N. V.
dc.contributor.authorIsaeva, E. V.
dc.contributor.authorKisel, A. A.
dc.contributor.authorBeketov, E. E.
dc.contributor.authorKomarova, L. N.
dc.contributor.authorAstakhina, S. O.
dc.contributor.authorКомарова, Людмила Николаевна
dc.contributor.authorАстахина, Светлана Олеговна
dc.date.accessioned2024-12-28T08:52:39Z
dc.date.available2024-12-28T08:52:39Z
dc.date.issued2023
dc.description.abstractGelatin methacryloyl (GelMA) has recently attracted increasing attention. Unlike other hydrogels, it allows for the adjustment of the mechanical properties using such factors as degree of functionalization, concentration, and photocrosslinking parameters. In this study, GelMA with a high degree of substitution (82.75 В± 7.09%) was synthesized, and its suitability for extrusion printing, cytocompatibility, and biocompatibility was studied. Satisfactory printing quality was demonstrated with the 15% concentration hydrogel. The high degree of functionalization led to a decrease in the ability of human adipose-derived stem cells (ADSCs) to adhere to the GelMA surface. During the first 3 days after sowing, proliferation was observed. Degradation in animals after subcutaneous implantation was slowed down.
dc.identifier.citationProperties and Printability of the Synthesized Hydrogel Based on GelMA / Arguchinskaya, N. V. [et al.] // International Journal of Molecular Sciences. - 2023. - 24. - № 3. - 10.3390/ijms24032121
dc.identifier.doi10.3390/ijms24032121
dc.identifier.urihttps://www.doi.org/10.3390/ijms24032121
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85147894061&origin=resultslist
dc.identifier.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000931064600001
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/29955
dc.relation.ispartofInternational Journal of Molecular Sciences
dc.subjectBiocompatibility
dc.subjectGelatin
dc.subjectSurface modification
dc.subjectHydrogels
dc.titleProperties and Printability of the Synthesized Hydrogel Based on GelMA
dc.typeArticle
dspace.entity.typePublication
oaire.citation.issue3
oaire.citation.volume24
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relation.isAuthorOfPublication0de0f37b-db32-4b8f-992c-6eab0513e7da
relation.isAuthorOfPublication.latestForDiscovery567c4324-7a87-4d82-a6f6-7320d0d475ad
relation.isOrgUnitOfPublication4b108cd7-08a1-4350-ab3f-20450dec091d
relation.isOrgUnitOfPublication.latestForDiscovery4b108cd7-08a1-4350-ab3f-20450dec091d
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