Publication: Properties and Printability of the Synthesized Hydrogel Based on GelMA
Дата
2023
Авторы
Arguchinskaya, N. V.
Isaeva, E. V.
Kisel, A. A.
Beketov, E. E.
Komarova, L. N.
Astakhina, S. O.
Journal Title
Journal ISSN
Volume Title
Издатель
Аннотация
Gelatin methacryloyl (GelMA) has recently attracted increasing attention. Unlike other hydrogels, it allows for the adjustment of the mechanical properties using such factors as degree of functionalization, concentration, and photocrosslinking parameters. In this study, GelMA with a high degree of substitution (82.75 В± 7.09%) was synthesized, and its suitability for extrusion printing, cytocompatibility, and biocompatibility was studied. Satisfactory printing quality was demonstrated with the 15% concentration hydrogel. The high degree of functionalization led to a decrease in the ability of human adipose-derived stem cells (ADSCs) to adhere to the GelMA surface. During the first 3 days after sowing, proliferation was observed. Degradation in animals after subcutaneous implantation was slowed down.
Описание
Ключевые слова
Biocompatibility , Gelatin , Surface modification , Hydrogels
Цитирование
Properties and Printability of the Synthesized Hydrogel Based on GelMA / Arguchinskaya, N. V. [et al.] // International Journal of Molecular Sciences. - 2023. - 24. - № 3. - 10.3390/ijms24032121
URI
https://www.doi.org/10.3390/ijms24032121
https://www.scopus.com/record/display.uri?eid=2-s2.0-85147894061&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000931064600001
https://openrepository.mephi.ru/handle/123456789/29955
https://www.scopus.com/record/display.uri?eid=2-s2.0-85147894061&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000931064600001
https://openrepository.mephi.ru/handle/123456789/29955