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fmri and tractographic studies of cognitive systems in the human brain at the norm and the paranoid schizophrenia

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dc.contributor.authorOrlov, V. A.
dc.contributor.authorMalakhov, D. G.
dc.contributor.authorMaslennikova, A. V.
dc.contributor.authorArkhipov, A. Y.
dc.contributor.authorUshakov, V. L.
dc.contributor.authorKartashov, S. I.
dc.contributor.authorУшаков, Вадим Леонидович
dc.date.accessioned2024-11-18T15:42:21Z
dc.date.available2024-11-18T15:42:21Z
dc.date.issued2019
dc.description.abstract© Springer Nature Switzerland AG 2019. This study is aimed at a systematic study of the work of neural networks of the human brain and their architecture in norm and in schizophrenia. To obtain the neurophysiological data, a unique complex of experimental equipment for world-class neurocognitive studies was used. The data obtained showed a significant decrease in the structural connectivity relationships for the rich club coefficient for a group of schizophrenic patients compared with the norm. Perception of emotionally negative visual and audio stimuli related to delusions in patients with schizophrenia does not lead to a significant decrease in BOLD signal as compared with the norm in Calcarine_L, Cerebelum_4_5_R, ParaHippocampal_LR, Precuneus_L, Temporal_Sup_R areas. The differences found in the structural and functional patterns of cognitive-affective disorders can serve as prognostic biomarkers in patients with schizophrenia and will make a significant contribution to the development of high-tech diagnostics in the early stages of mental illness.
dc.format.extentС. 291-299
dc.identifier.citationfmri and tractographic studies of cognitive systems in the human brain at the norm and the paranoid schizophrenia / Orlov,V.A. [et al.] // Studies in Computational Intelligence. - 2019. - 799. - P. 291-299. - 10.1007/978-3-030-01328-8_35
dc.identifier.doi10.1007/978-3-030-01328-8_35
dc.identifier.urihttps://www.doi.org/10.1007/978-3-030-01328-8_35
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85054650985&origin=resultslist
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/16337
dc.relation.ispartofStudies in Computational Intelligence
dc.titlefmri and tractographic studies of cognitive systems in the human brain at the norm and the paranoid schizophrenia
dc.typeConference Paper
dspace.entity.typePublication
oaire.citation.volume799
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