Publication:
Photodynamic therapy of classic Kaposi's sarcoma with video-fluorescence control

Дата
2021
Авторы
Shiryaev, A. A.
Kornev, D. O.
Samoylova, S. I.
Fatyanova, A. S.
Efendiev, K. T.
Loschenov, V. B.
Journal Title
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Научные группы
Организационные подразделения
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Организационная единица
Инженерно-физический институт биомедицины
Цель ИФИБ и стратегия развития – это подготовка высококвалифицированных кадров на базе передовых исследований и разработок новых перспективных методов и материалов в области инженерно-физической биомедицины. Занятие лидерских позиций в биомедицинских технологиях XXI века и внедрение их в образовательный процесс, что отвечает решению практикоориентированной задачи мирового уровня – диагностике и терапии на клеточном уровне социально-значимых заболеваний человека.
Выпуск журнала
Аннотация
© 2021 Elsevier B.V.Background: Kaposi's sarcoma (multiple idiopathic hemorrhagic sarcoma, Kaposi's angiosarcoma) is an angioproliferative neoplasm of endothelial origin associated with human herpes virus 8 (HHV – 8) and human immunodeficiency virus (HIV). The incidence of the classical form of Kaposi's sarcoma (КS) varies significantly in different geographical areas from 0.14/1 million people (both men and women) to 10.5 per 1 million men and 2.7 per 1 million women. The onset of КS is typical at the age of 35–39 in men and 25–39 years in women. Case report: A case of successful treatment of a recurrent non-HIV and non-HHV-8 Kaposi's sarcoma with PDT in a 79-year old man. Results: After the recieved photodynamic treatment, complete pathologic response was achieved, i.e., Grade 5 tumor response according to Miller-Payne histological grading system (1999). The overall condition has significantly improved with no clinical tumor signs. Conclusion: This report describes a good outcome with PDT in the treatment of Kaposi's sarcoma. The results obtained are initial, but encouraging, demonstrating good tolerance, safety and high efficacy of PDT in classical КS. The successful use of PDT in cutaneous manifestations of HIV-associated KS is also described in literature.
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Photodynamic therapy of classic Kaposi's sarcoma with video-fluorescence control / Shiryaev, A.A. [et al.] // Photodiagnosis and Photodynamic Therapy. - 2021. - 35. - 10.1016/j.pdpdt.2021.102378
URI
https://www.doi.org/10.1016/j.pdpdt.2021.102378
 https://www.scopus.com/record/display.uri?eid=2-s2.0-85107802812&origin=resultslist
 http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000694915500005
 https://openrepository.mephi.ru/handle/123456789/24187
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