Персона: Комарова, Людмила Николаевна
Загружается...
Email Address
Birth Date
Научные группы
Организационные подразделения
Организационная единица
ИАТЭ НИЯУ МИФИ
ИАТЭ НИЯУ МИФИ был образован в 1953 г. как вечернее отделение МИФИ. В 2009 г. ИАТЭ официально получил статус обособленного структурного подразделения НИЯУ «МИФИ», что дало новый мощный импульс для развития образовательной и научной деятельности на основе инновационной составляющей. В соответствии с лицензией Минобрнауки России ИАТЭ ведет образовательную деятельность в рамках очной, очно-заочной и заочной форм обучения. В настоящее время в ИАТЭ НИЯУ МИФИ осуществляется подготовка по очной форме обучения: бакалавриат- 16 направлений, специалитет – 4 направления, магистратура- 12 направлений; по очно-заочной: бакалавриат- 4 направления, специалитет – 1 направление; по заочной: бакалавриат- 3 направления, специалитет- 2 направления; аспирантура – 18 направлений.
В структуре ИАТЭ 9 факультетов: физико-энергетический, естественных наук, кибернетики, социально-экономический, медицинский, вечерний, заочного обучения, подготовительный, повышения квалификации и профессиональной переподготовки специалистов. Образовательный процесс обеспечивают 18 общеобразовательных и 22 выпускающие кафедры.
Статус
Фамилия
Комарова
Имя
Людмила Николаевна
Имя
4 results
Результаты поиска
Теперь показываю 1 - 4 из 4
- ПубликацияТолько метаданныеSynergetic effects of the combined action of carbon ions and the chemotherapy drug doxorubicin on HeLa cancer cells(2021) Komarova, L. N.; Melnikova, A. A.; Baldov, D. A.; Комарова, Людмила Николаевна; Мельникова, Анжелика Александровна
- ПубликацияТолько метаданныеINVESTIGATION OF THE COMBINED EFFECT OF IONIZING RADIATION OF DIFFERENT QUALITY AND DOXORUBICIN ON BREAST ADENOCARCINOMA CELLS(2021) Komarova, L. N.; Melnikova, A. A.; Комарова, Людмила Николаевна; Мельникова, Анжелика Александровна© 2021 RAD Association. All rights reserved.The purpose of this work was to study the nature of the combined effect of ionizing radiation of accelerated 12C ions with the antitumor agent doxorubicin on malignant cells. In the course of the research, new results were obtained on the manifestation of the synergistic character of the interaction of the agents used on the cells of the MCF-7 tumor line, which is of important practical and theoretical significance for understanding the mechanism of the combined effect of ionizing radiation and the chemotherapy drug doxorubicin. The obtained data will help to optimize the combined effects in order to achieve maximum synergistic interaction.
- ПубликацияТолько метаданныеSynergetic effects of the combined action of carbon ions and the chemotherapy drug doxorubicin on hela cancer cells(2021) Komarova, L. N.; Mel’nikova, A. A.; Baldov, D. A.; Комарова, Людмила Николаевна; Мельникова, Анжелика Александровна© 2021 Obninsk Institute for Nuclear Power Engineering, National Research Nuclear University 'MEPhI'. All rights reserved.Proton and carbon beam therapy is currently recognized as the most effective and highly accurate form of radiation therapy for deeply located tumors, including radioresistant ones. This is due to the fact that they have all the advantages of spatial dose distribution and, at the same time, are densely ionizing radiations capable of effectively affecting hypoxic, slow"growing tumors and other neoplasms that are insensitive to traditional types of radiation. It is well known that one of the main methods for treating neoplasms is chemotherapy. The predominant mechanism of action of anti"tumor drugs is the induction of DNA damage with the subsequent impossibility of repair. In our study, we used an anti"tumor antibiotic of the anthracycline series, doxorubicin. The assessment of the potential significance of the synergistic interaction of ionizing radiation with chemical preparations in medical radiology remains an urgent and unresolved problem. It is possible to achieve the maximum effect of the combined action of two agents when they act simultaneously. The phenomenon of synergy can be used to optimize the combined use of radiation and chemotherapy in clinical practice. In this regard, it seems relevant to conduct a study for HeLa cancer cells exposed to ionizing radiation, an antitumor drug, as well as their combination. In the course of the study, results were obtained on the manifestation of the synergistic nature of the agents used, which is of great practical and theoretical importance for understanding the mechanism of the combined effect of ionizing radiation and the chemotherapy drug (doxorubicin). The obtained data can be helpful in optimizing the combined effects in order to achieve maximum synergistic interaction.
- ПубликацияОткрытый доступContribution of foodstuffs contained radionuclides to formation of internal radiation doses received in areas Bryansk region affected by the Chernobyl accident Вклад содержащих радионуклиды пищевых продуктов в формирование доз внутреннего облучения населения юго-запада Брянскои области после аварии на Чернобыльскои АЭС(2023) Panov, A. V.; Komarova L. N.; Lyapunova E. R.; Mel’nikova A. A.; Комарова, Людмила Николаевна; Мельникова, Анжелика АлександровнаThe authors review current specific features of internal radiation doses received by people resided in 135 urban and rural settlements in six south-western districts of the Bryansk region affected by the Chernobyl accident. The residents received the average annual radiation dose andgt; 1 mSv. The Cs-137 radioactivity contained in local agricultural and natural food was evaluated with the account of the dietary structure. Comparative analysis of long-term data on a contribution of local food contained radionuclides to the population, estimated by the average annual effective dose of internal radiation was carried out. Potatoes and pork taken from the private farms in the settlements under survey met health and hygiene standards for different levels of Cs-137 in 2022. However, there was a risk of exceeding the sanitary hygiene’s requirements for Cs-137 specific radioactivity in milk from privately-owned farms located in 89% of the settlements under survey, in 98% of beef produced in the farms and in 100% of mushrooms collected in forests near these settlements. Currently, the main dose-forming product is milk (contribution to the internal exposure dose is 60%), a smaller role in dose formation is in mushrooms (about 20%) and a minimal dose is in potatoes and meat (10% each). Over the past 20 years, the contribution of milk to the internal exposure dose has increased by 15-20%, and the contribution of mushrooms has decreased because of changes in the diet of the rural population of the Bryansk region and due to the reduction and redistribution of local products in the food basket.