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AFM-MS for Protein Analysis of Plasma Samples of Patients with Ovarian Cancer

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dc.contributor.authorKaysheva, A. L.
dc.contributor.authorPleshakova, T. O.
dc.contributor.authorMalsagova, K. A.
dc.contributor.authorChingin, K.
dc.contributor.authorPronichev, A. N.
dc.contributor.authorNikitaev, V. G.
dc.contributor.authorIvanov, E. O.
dc.contributor.authorПроничев, Александр Николаевич
dc.contributor.authorНикитаев, Валентин Григорьевич
dc.date.accessioned2024-11-21T12:08:22Z
dc.date.available2024-11-21T12:08:22Z
dc.date.issued2019
dc.description.abstractAn atomic force microscope (AFM) is a molecular detector that allows the recording of individual proteins and protein complexes on the surface of an atomically flat substrate, the AFM chip. Registration of target proteins is carried out after the fishing procedure - catching out of proteins from the volume of the analyzed solution to a surface of a small area (sensory zone of the chip) modified by affinity reagents against the target protein. The use of the procedure of biospecific enrichment makes it possible to effectively concentrate the molecules of the target proteins in an amount sufficient for the subsequent mass spectrometric analysis for early diagnosis of ovarian cancer in blood samples.
dc.format.extentС. 267-271;
dc.identifier.citationAFM-MS for Protein Analysis of Plasma Samples of Patients with Ovarian Cancer / Kaysheva, AL [et al.] // Bulletin of the Lebedev Physics Institute. - 2019. - 46. - № 8. - P. 267-271;. - 10.3103/S1068335619080074
dc.identifier.doi10.3103/S1068335619080074
dc.identifier.urihttps://www.doi.org/10.3103/S1068335619080074
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85072989191&origin=resultslist
dc.identifier.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000485900400007
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/18712
dc.relation.ispartofBulletin of the Lebedev Physics Institute
dc.titleAFM-MS for Protein Analysis of Plasma Samples of Patients with Ovarian Cancer
dc.typeArticle
dspace.entity.typePublication
oaire.citation.issue8
oaire.citation.volume46
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