Publication: Tractographic studies in the human brain at the norm and the paranoid schizophrenia
Дата
2021
Авторы
Kartashov, S. I.
Vartanov, A. V.
Zakharova, N. V.
Arkhipov, A. Y.
Ushakov, V. L.
Journal Title
Journal ISSN
Volume Title
Издатель
Аннотация
© 2020 Elsevier B.V.. All rights reserved.This study is part of a large interdisciplinary project to create objective criteria for building a classification system for a polymorphic schizophrenic disease characterized by disorders of thinking and perception. Within the framework of the project, for the first time in patients with schizophrenia with hallucinatory-delusional syndrome, neuropsychological testing, complete structural (morphometry and tractography) and functional MRI studies involving a detailed clinical study, determination of the patient's immunological and genetic status are simultaneously performed. On the basis of a comprehensive analysis of MRI data, it is planned to determine the key architecture of the neural networks of the brain producing the disease, to assess the success of disease therapy and to determine the targets of subsequent therapy based on the application of the method of transcranial magnetic stimulation. This paper presents the primary results of work on the study of the difference between the structural connectomes of schizophrenic patients and the norm. The work is of a search and preliminary nature. As a result of the work, the possibility of classifying the disease was shown and the key structural links for it were identified.
Описание
Ключевые слова
Цитирование
Tractographic studies in the human brain at the norm and the paranoid schizophrenia / Kartashov, S.I. [et al.] // Procedia Computer Science. - 2021. - 190. - P. 434-438. - 10.1016/j.procs.2021.06.051