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Influence of Powerful Non-Ionizing Terahertz Radiation on Healthy and Tumor Human Cells of Neural Origin ВЛИЯНИЕ МОЩНОГО НЕИОНИЗИРУЮЩЕГО ТЕРАГЕРЦОВОГО ИЗЛУЧЕНИЯ НА ЗДОРОВЫЕ И ОПУХОЛЕВЫЕ КЛЕТКИ ЧЕЛОВЕКА НЕИРАЛЬНОГО ПРОИСХОЖДЕНИЯ

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dc.contributor.authorRevkova, V. A.
dc.contributor.authorIlina, I. V.
dc.contributor.authorSitnikov, D. S.
dc.contributor.authorShatalova, R. O.
dc.contributor.authorGurova, S. A.
dc.date.accessioned2024-11-30T02:46:46Z
dc.date.available2024-11-30T02:46:46Z
dc.date.issued2021
dc.description.abstract© 2021 State Research Center, Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. All rights reserved.Purpose: Study of the influence of high-power pulses of coherent non-ionizing terahertz (THz) radiation on the formation of foci of double-strand DNA breaks and the proliferative activity of human neuronal cells. Material and methods: Irradiated cell cultures are direct reprogramming neural progenitor cells (drNPCs), neuroblastoma cells (SKN-BE). Cells are irradiated with a sequence of THz radiation pulses with a peak intensity of ~ 20 GW/cm2 and electric field strength of 2.8 MV/cm. Irradiation lasts 30 mins. Results: There is no statistically significant difference in the number of γH2AX histone foci between experimental and control cell groups. Conclusion: It was shown that a short exposure (30 min) of cells to THz radiation with intensity of 20 GW/cm2 does not affect the proliferative activity of both neural progenitor cells and neuroblastoma cells and does not cause a significant increase in γH2AX foci in any of the studied cell lines.
dc.format.extentС. 5-10
dc.identifier.citationInfluence of Powerful Non-Ionizing Terahertz Radiation on Healthy and Tumor Human Cells of Neural Origin ВЛИЯНИЕ МОЩНОГО НЕИОНИЗИРУЮЩЕГО ТЕРАГЕРЦОВОГО ИЗЛУЧЕНИЯ НА ЗДОРОВЫЕ И ОПУХОЛЕВЫЕ КЛЕТКИ ЧЕЛОВЕКА НЕИРАЛЬНОГО ПРОИСХОЖДЕНИЯ / Revkova, V.A. [et al.] // Medical Radiology and Radiation Safety. - 2021. - 66. - № 5. - P. 5-10. - 10.12737/1024-6177-2021-66-5-5-10
dc.identifier.doi10.12737/1024-6177-2021-66-5-5-10
dc.identifier.urihttps://www.doi.org/10.12737/1024-6177-2021-66-5-5-10
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85122567008&origin=resultslist
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/25306
dc.relation.ispartofMedical Radiology and Radiation Safety
dc.titleInfluence of Powerful Non-Ionizing Terahertz Radiation on Healthy and Tumor Human Cells of Neural Origin ВЛИЯНИЕ МОЩНОГО НЕИОНИЗИРУЮЩЕГО ТЕРАГЕРЦОВОГО ИЗЛУЧЕНИЯ НА ЗДОРОВЫЕ И ОПУХОЛЕВЫЕ КЛЕТКИ ЧЕЛОВЕКА НЕИРАЛЬНОГО ПРОИСХОЖДЕНИЯ
dc.typeArticle
dspace.entity.typePublication
oaire.citation.issue5
oaire.citation.volume66
relation.isOrgUnitOfPublication4b108cd7-08a1-4350-ab3f-20450dec091d
relation.isOrgUnitOfPublication.latestForDiscovery4b108cd7-08a1-4350-ab3f-20450dec091d
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