Publication:
Refinement of Animal Experiments: Replacing Traumatic Methods of Laboratory Animal Marking with Non-Invasive Alternatives

Простая страница элемента
dc.contributor.authorKlabukov, I.
dc.contributor.authorShestakova, V.
dc.contributor.authorKrasilnikova, O.
dc.contributor.authorSmirnova, A.
dc.date.accessioned2024-12-27T11:52:22Z
dc.date.available2024-12-27T11:52:22Z
dc.date.issued2023
dc.description.abstractReliable methods for identifying rodents play an important role in ensuring the success of preclinical studies. However, animal identification remains a trivial laboratory routine that is not often discussed, despite the fact that more than 6 million rodents are used in animal studies each year. Currently, there are extensive regulations in place to ensure adequate anesthesia and to reduce animal suffering during experiments. At the same time, not enough attention is paid to the comfort of rodents during routine identification procedures, which can be painful and cause some complications. In order to achieve the highest ethical standards in laboratory research, we must minimize animal discomfort during the identification phase. In this article, we discuss traumatic methods of identification and describe several painless methods for marking in long-term experimental studies. The use of non-traumatic and non-invasive methods requires the renewal of marks as they fade and additional handling of the rodents. Laboratory personnel must be trained in stress-minimizing handling techniques to make mark renewal less stressful.
dc.identifier.citationRefinement of Animal Experiments: Replacing Traumatic Methods of Laboratory Animal Marking with Non-Invasive Alternatives / Klabukov, I. [et al.] // Animals. - 2023. - 13. - № 22. - 10.3390/ani13223452
dc.identifier.doi10.3390/ani13223452
dc.identifier.urihttps://www.doi.org/10.3390/ani13223452
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85178364180&origin=resultslist
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/29477
dc.relation.ispartofAnimals
dc.subjectIdentification (biology)
dc.subjectAnimal testing
dc.subjectAnimal Research Reporting
dc.subjectAnimal Research
dc.subjectRodent Eradication
dc.subjectPreclinical Studies
dc.subjectAnimal species
dc.subjectAnimal model
dc.titleRefinement of Animal Experiments: Replacing Traumatic Methods of Laboratory Animal Marking with Non-Invasive Alternatives
dc.typeReview
dspace.entity.typePublication
oaire.citation.issue22
oaire.citation.volume13
relation.isOrgUnitOfPublication4b108cd7-08a1-4350-ab3f-20450dec091d
relation.isOrgUnitOfPublication.latestForDiscovery4b108cd7-08a1-4350-ab3f-20450dec091d
Файлы
Original bundle
Теперь показываю 1 - 1 из 1
Уменьшенное изображение
Name:
animals-13-03452.pdf
Size:
544.44 KB
Format:
Adobe Portable Document Format
Description:
Download
Коллекции
Публикации