Publication: Mueller-matrix-based polarization imaging and quantitative assessment of optically anisotropic polycrystalline networks
Дата
2019
Авторы
Borovkova, M.
Trifonyuk, L.
Ushenko, V.
Dubolazov, O.
Meglinski, I.
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Аннотация
© 2019 Borovkova et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. We introduce a Mueller-matrix imaging polarization-based approach for the quantitative digital screening of the polycrystalline structure of fibrillary-based biological tissues in vitro. The morphometric evaluation of histological sections of myocardium was performed utilizing the high-order statistical moments calculated based on the spatial distribution of linear and circular birefringence and dichroism obtained experimentally. We demonstrate that spatial distributions of phase of light and optical anisotropy of scattering inherent to fibrillar networks of myocardium at different necrotic stages can be effectively used as a quantitative marker of stages of myosin fibril degradation. Processing the images of phase of light scattered in biological tissues with high order statistical analysis provides a functional tool for the quantitative characterization of necrotic conditions of the myocardium.
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Цитирование
Mueller-matrix-based polarization imaging and quantitative assessment of optically anisotropic polycrystalline networks / Borovkova, M. [et al.] // PLoS ONE. - 2019. - 14. - № 5. - 10.1371/journal.pone.0214494
URI
https://www.doi.org/10.1371/journal.pone.0214494
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https://openrepository.mephi.ru/handle/123456789/18057
https://www.scopus.com/record/display.uri?eid=2-s2.0-85065917520&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000468030100010
https://openrepository.mephi.ru/handle/123456789/18057