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Laser-ablative synthesis of nanomaterials for nuclear and radiative medicine applications

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dc.contributor.authorTikhonowski, G. V.
dc.contributor.authorPopov, A. A.
dc.contributor.authorZelepukin, I.
dc.contributor.authorPopova-Kuznetsova, E.
dc.contributor.authorDombrovska, Y.
dc.contributor.authorDeyev, S. M.
dc.contributor.authorZavestovskaya, I. N.
dc.contributor.authorKlimentov, S. M.
dc.contributor.authorPrasad, P. N.
dc.contributor.authorKabashin, A. V.
dc.contributor.authorТихоновский, Глеб Валерьевич
dc.contributor.authorПопов, Антон Александрович
dc.contributor.authorПопова-Кузнецова, Елена Алефтиновна
dc.contributor.authorДеев, Сергей Михайлович
dc.contributor.authorЗавестовская, Ирина Николаевна
dc.contributor.authorКлиментов, Сергей Михайлович
dc.contributor.authorКабашин, Андрей Викторович
dc.date.accessioned2024-12-25T19:23:36Z
dc.date.available2024-12-25T19:23:36Z
dc.date.issued2022
dc.description.abstractNewly emerging nanomaterials promise a major advancement of methods of nuclear and radiative medicine for cancer treatment, as they can be used as carriers of diagnostic or therapeutic radionuclides, contrast agents in nuclear imaging modalities (PET, SPECT) or sensitizers of radiative therapies (X-ray, ion beams, etc.). However, nanotechnology-based approaches have reported a limited success so far due to a lack of suitable functional nanoformulations, which are safe, non-toxic, excretable from the body and have favorable pharmacokinetics for effective accumulation in the tumor. As follows from the results of our on-going research activities, many of the above-stated problems can we solved by the employment of nanomaterials fabricated by clean laser-ablative synthesis. Here, we review our recent data on some promising nanomaterials, prepared by this method, including biodegradable silicon (Si) nanoparticles (NPs), Sm-152-enriched samarium oxide NPs, and elemental bismuth (Bi) NPs, which can be used either as carriers/agents in radionuclide therapy, or sensitizers in radiative diagnostics or therapy. Advantages of proposed approach include exceptional purity and flexibility in synthesizing of NPs of required physico-chemical parameters (controlled size, shape, composition, and surface conditioning of NPs). Advances in laser-ablative fabrication of novel nanomaterials open up avenues for future implementations of nuclear and radiative medicine approaches for safe and efficient theranostics of tumors and metastasis.
dc.identifier.citationLaser-ablative synthesis of nanomaterials for nuclear and radiative medicine applications / (лаббиофот) Tikhonowski, G. V. [et al.] // NANOSCALE AND QUANTUM MATERIALS: FROM SYNTHESIS AND LASER PROCESSING TO APPLICATIONS 2022. - 2022. - 11990. - 10.1117/12.2615386
dc.identifier.doi10.1117/12.2615386
dc.identifier.urihttps://www.doi.org/10.1117/12.2615386
dc.identifier.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000844464500009
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/28474
dc.relation.ispartofNANOSCALE AND QUANTUM MATERIALS: FROM SYNTHESIS AND LASER PROCESSING TO APPLICATIONS 2022
dc.titleLaser-ablative synthesis of nanomaterials for nuclear and radiative medicine applications
dc.typeProceedings Paper
dspace.entity.typePublication
oaire.citation.volume11990
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