Publication: Outflow Kinetics of Chemical Solutions from Hydrophobized Nanostructural Silicon Compounds: Effect of Surface Tension
Дата
2021
Авторы
Shimanovsky, N. L.
Belogorlov, A. A.
Khrebtov, D. S.
Bortnikova, S. A.
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Аннотация
© 2021, Springer Science+Business Media, LLC, part of Springer Nature.The outflow kinetics of aqueous solutions of n-propanol as model liquids (drug solutions) from hydrophobic nanoporous silica gel 60 C8 was studied. The solution surface tension was shown to influence the hysteresis of intrusion-extrusion pressures and outflow rate. The use of substances changing the surface tension of the injected solution, in particular doxorubicin, allows one to control the relaxation/release of doxorubicin molecules in/from the focus of the disorder at the optimum rate. The obtained results can be used to create drug delivery systems based on silicon nanoparticles.
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Цитирование
Outflow Kinetics of Chemical Solutions from Hydrophobized Nanostructural Silicon Compounds: Effect of Surface Tension / Shimanovsky, N.L. [et al.] // Pharmaceutical Chemistry Journal. - 2021. - 10.1007/s11094-021-02383-3
URI
https://www.doi.org/10.1007/s11094-021-02383-3
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https://openrepository.mephi.ru/handle/123456789/24133
https://www.scopus.com/record/display.uri?eid=2-s2.0-85105621688&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000646483700012
https://openrepository.mephi.ru/handle/123456789/24133