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Engineering of fluorescent biomaging tools for cancer cell targeting based on polyelectrolyte microcapsules encoded with quantum dots

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dc.contributor.authorRamos-Gomes, F.
dc.contributor.authorAlves, F.
dc.contributor.authorSukhanova, A.
dc.contributor.authorNifontova, G.
dc.contributor.authorBaryshnikova, M.
dc.contributor.authorNabiev, I.
dc.contributor.authorНифонтова, Галина Олеговна
dc.contributor.authorБарышникова, Мария Анатольевна
dc.contributor.authorНабиев, Игорь Руфаилович
dc.date.accessioned2024-11-22T06:54:32Z
dc.date.available2024-11-22T06:54:32Z
dc.date.issued2019
dc.description.abstract© 2019 SPIE.Quantum dots (QDs) are fluorescent semiconductor nanocrystals with a high photostability, wide absorption spectra, and narrow, size-tunable emission spectra, which make them promising nanolabels to be encapsulated in microcarriers used as bioimaging and theranostic tools. Here, we describe an approach to the optical encoding of polyelectrolyte microcapsules with the prepared stable water-soluble QDs and key stages of surface functionalization of these microcapsules with cetuximab, humanised monoclonal anticancer antibody. Obtained conjugates demonstrate the specificity and efficiency of the engineered system as a cancer cell-targeted tracing tool that could be used for cancer diagnosis, treatment and monitoring of cancer therapy.
dc.identifier.citationEngineering of fluorescent biomaging tools for cancer cell targeting based on polyelectrolyte microcapsules encoded with quantum dots / Ramos-Gomes, F. [et al.] // Proceedings of SPIE - The International Society for Optical Engineering. - 2019. - 11207. - 10.1117/12.2530281
dc.identifier.doi10.1117/12.2530281
dc.identifier.urihttps://www.doi.org/10.1117/12.2530281
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85074274410&origin=resultslist
dc.identifier.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000535234000085
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/19743
dc.relation.ispartofProceedings of SPIE - The International Society for Optical Engineering
dc.titleEngineering of fluorescent biomaging tools for cancer cell targeting based on polyelectrolyte microcapsules encoded with quantum dots
dc.typeConference Paper
dspace.entity.typePublication
oaire.citation.volume11207
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