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Magnetofection in vivo by nanomagnetic carriers systemically administered into the bloodstream

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dc.contributor.authorSizikov, A. A.
dc.contributor.authorNikitin, M. P.
dc.contributor.authorNikitin, P. I.
dc.contributor.authorНикитин, Петр Иванович
dc.date.accessioned2024-11-29T23:59:41Z
dc.date.available2024-11-29T23:59:41Z
dc.date.issued2021
dc.description.abstract© 2021 by the authors. Licensee MDPI, Basel, Switzerland.Nanoparticle-based technologies are rapidly expanding into many areas of biomedicine and molecular science. The unique ability of magnetic nanoparticles to respond to the magnetic field makes them especially attractive for a number of in vivo applications including magnetofection. The magnetofection principle consists of the accumulation and retention of magnetic nanoparticles carrying nucleic acids in the area of magnetic field application. The method is highly promising as a clinically efficient tool for gene delivery in vivo. However, the data on in vivo magnetofection are often only descriptive or poorly studied, insufficiently systematized, and sometimes even contra-dictory. Therefore, the aim of the review was to systematize and analyze the data that influence the in vivo magnetofection processes after the systemic injection of magnetic nanostructures. The main emphasis is placed on the structure and coating of the nanomagnetic vectors. The present problems and future trends of the method development are also considered.
dc.identifier.citationSizikov, A. A. Magnetofection in vivo by nanomagnetic carriers systemically administered into the bloodstream / Sizikov, A.A., Nikitin, M.P., Nikitin, P.I. // Pharmaceutics. - 2021. - 13. - № 11. - 10.3390/pharmaceutics13111927
dc.identifier.doi10.3390/pharmaceutics13111927
dc.identifier.urihttps://www.doi.org/10.3390/pharmaceutics13111927
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85119602444&origin=resultslist
dc.identifier.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000725038000001
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/25044
dc.relation.ispartofPharmaceutics
dc.titleMagnetofection in vivo by nanomagnetic carriers systemically administered into the bloodstream
dc.typeReview
dspace.entity.typePublication
oaire.citation.issue11
oaire.citation.volume13
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