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Cost-effective device for locating and circumscribing superficial tumors with contrast enhancement and fluorescence quantification

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dc.contributor.authorUdeneev, A. M.
dc.contributor.authorKalyagina, N. A.
dc.contributor.authorEfendiev, K. T.
dc.contributor.authorFebenchukova, A. A.
dc.contributor.authorKulichenko, A. M.
dc.contributor.authorLoshchenov, M. V.
dc.contributor.authorКалягина, Нина Анатольевна
dc.contributor.authorЭфендиев, Канамат Темботович
dc.contributor.authorЛощенов, Максим Викторович
dc.date.accessioned2024-12-04T08:15:19Z
dc.date.available2024-12-04T08:15:19Z
dc.date.issued2024
dc.description.abstractTwo Bispectral contrast enhancement approaches for the fluorescence diagnosis with chlorine-e6 and a wide field-of-view imaging system with fluorescence excitation at 405 nm and time-resolved background suppression were analyzed and compared. Two techniques for the contrast enhancement of a fluorescent video system (Red/Green (R/G) ratio and Red-Green (R-G)) with time-resolved background suppression for fluorescent diagnosis (FD) were tested in four patients with basal cell carcinoma (BCC). The results of both contrast enhancement methods were compared for the diagnostic efficiency for FD of BCC. Both techniques successfully determined the boundaries of the lesions and the fluorescence intensity. Both contrast enhancement modes have proven effective in identifying tumor borders in cases of low contrast in BCC FD with Ce6. While the Red/Green (R/G) mode provides sharper lesion borders, the Red minus Green (R-G) mode visualizes more fluorescent features and makes it easier to assess the lesion margins.
dc.identifier.citationCost-effective device for locating and circumscribing superficial tumors with contrast enhancement and fluorescence quantification / Udeneev, A.M., [et al.] // Photodiagnosis and Photodynamic Therapy. - 2024. - 10.1016/j.pdpdt.2023.103827
dc.identifier.doi10.1016/j.pdpdt.2023.103827
dc.identifier.urihttps://www.doi.org/10.1016/j.pdpdt.2023.103827
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85174531996&origin=resultslist
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/25728
dc.relation.ispartofPhotodiagnosis and Photodynamic Therapy
dc.subjectContrast enhancement
dc.subjectContrast Agents
dc.subjectTumor Imaging
dc.subjectCancer Detection
dc.subjectMicrovasculature Detection
dc.subjectTissue Optical Clearing
dc.titleCost-effective device for locating and circumscribing superficial tumors with contrast enhancement and fluorescence quantification
dc.typeArticle
dspace.entity.typePublication
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