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Clinical significance of sflt-1/plgf in the diagnosis and prediction of preeclampsia

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dc.contributor.authorGuryeva, V. M.
dc.contributor.authorTravkina, A. A.
dc.contributor.authorMatveev, M. O.
dc.contributor.authorMorokhotova, L. S.
dc.contributor.authorSemenova, T. A.
dc.contributor.authorСеменова, Татьяна Алексеевна
dc.date.accessioned2024-11-29T19:29:01Z
dc.date.available2024-11-29T19:29:01Z
dc.date.issued2021
dc.description.abstract© A group of authors, 2021.The diagnosis of preeclampsia in clinical practice causes certain difficulties due to the non-specificity of symptoms, the polymorphism of the clinical picture, and the discrepancy between the magnitude of clinical symptoms and the severity of multiple organ dysfunction. Therefore, the accurate diagnosis and prediction of preeclampsia is of great importance for practical obstetrics. The paper presents the results of the basic studies devoted to the clinical interpretation of the sFlt-1/PlGF ratio for the diagnosis and prediction of preeclampsia and shows the informative value and significance of the ratio for the objectification of the diagnosis of preeclampsia, as well as the possibility of predicting this obstetric complication according to sFlt-1/PlGF data. It shows the experience of using sFlt-1/ PlGF in the obstetric service in the Moscow Region and formulates indications for the study of sFlt-1/PlGF in clinical practice and approaches to its interpretation. Conclusion. The application of sFlt-1/PlGF allows the differential diagnosis of preeclampsia with an exacerbation or a manifestation of a number of somatic diseases that occur with similar clinical symptoms. The use of sFlt-1/PlGF provides an economic effect, by improving the routing and decreasing the number of severe perinatal and maternal outcomes, as well as reducing unjustified hospitalization. sFlt-1/PlGF is an informative marker for the diagnosis and prediction of preeclampsia and its adverse outcomes and can be recommended for use in clinical practice.
dc.format.extentС. 195-200
dc.identifier.citationClinical significance of sflt-1/plgf in the diagnosis and prediction of preeclampsia / Guryeva, V.M. [et al.] // Akusherstvo i Ginekologiya (Russian Federation). - 2021. - 2021. - № 7. - P. 195-200. - 10.18565/aig.2021.7.195-200
dc.identifier.doi10.18565/aig.2021.7.195-200
dc.identifier.urihttps://www.doi.org/10.18565/aig.2021.7.195-200
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85113142586&origin=resultslist
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/24593
dc.relation.ispartofAkusherstvo i Ginekologiya (Russian Federation)
dc.titleClinical significance of sflt-1/plgf in the diagnosis and prediction of preeclampsia
dc.typeArticle
dspace.entity.typePublication
oaire.citation.issue7
oaire.citation.volume2021
relation.isAuthorOfPublicationb0a87f82-fbdb-46b3-ab2f-71ce9a954e25
relation.isAuthorOfPublication.latestForDiscoveryb0a87f82-fbdb-46b3-ab2f-71ce9a954e25
relation.isOrgUnitOfPublicationd19559ab-04cd-486a-ae8e-f40ccd36a1a6
relation.isOrgUnitOfPublication.latestForDiscoveryd19559ab-04cd-486a-ae8e-f40ccd36a1a6
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