Publication:
Biosensors Based on Inorganic Composite Fluorescent Hydrogels

dc.contributor.authorSokolov, P.
dc.contributor.authorSamokhvalov, P.
dc.contributor.authorSukhanova, A.
dc.contributor.authorNabiev, I.
dc.contributor.authorСоколов, Павел Михайлович
dc.contributor.authorСамохвалов, Павел Сергеевич
dc.contributor.authorНабиев, Игорь Руфаилович
dc.date.accessioned2024-12-28T11:42:35Z
dc.date.available2024-12-28T11:42:35Z
dc.date.issued2023
dc.description.abstractFluorescent hydrogels are promising candidate materials for portable biosensors to be used in point-of-care diagnosis because (1) they have a greater capacity for binding organic molecules than immunochromatographic test systems, determined by the immobilization of affinity labels within the three-dimensional hydrogel structure; (2) fluorescent detection is more sensitive than the colorimetric detection of gold nanoparticles or stained latex microparticles; (3) the properties of the gel matrix can be finely tuned for better compatibility and detection of different analytes; and (4) hydrogel biosensors can be made to be reusable and suitable for studying dynamic processes in real time. Water-soluble fluorescent nanocrystals are widely used for in vitro and in vivo biological imaging due to their unique optical properties, and hydrogels based on these allow the preservation of these properties in bulk composite macrostructures. Here we review the techniques for obtaining analyte-sensitive fluorescent hydrogels based on nanocrystals, the main methods used for detecting the fluorescent signal changes, and the approaches to the formation of inorganic fluorescent hydrogels via sol–gel phase transition using surface ligands of the nanocrystals.
dc.identifier.citationBiosensors Based on Inorganic Composite Fluorescent Hydrogels / Sokolov, P. [et al.] // Nanomaterials. - 2023. - 13. - № 11. - 10.3390/nano13111748
dc.identifier.doi10.3390/nano13111748
dc.identifier.urihttps://www.doi.org/10.3390/nano13111748
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85161861921&origin=resultslist
dc.identifier.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:001005397200001
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/30228
dc.relation.ispartofNanomaterials
dc.subjectBiosensor Applications
dc.subjectElectrochemical Biosensors
dc.subjectHydrogels
dc.subjectGlucose Sensors
dc.subjectNon-enzymatic Sensors
dc.titleBiosensors Based on Inorganic Composite Fluorescent Hydrogels
dc.typeReview
dspace.entity.typePublication
oaire.citation.issue11
oaire.citation.volume13
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