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Influence of 11C-MET PET acquisition time for differential diagnosis of human brain gliomas

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dc.contributor.authorVikhrova, N.
dc.contributor.authorBatalov, A.
dc.contributor.authorKonakova, T.
dc.contributor.authorKhokhlova, E.
dc.contributor.authorPostnov, A.
dc.contributor.authorKalaeva, D.
dc.contributor.authorКалаева, Диана Борисовна
dc.date.accessioned2024-11-29T23:26:47Z
dc.date.available2024-11-29T23:26:47Z
dc.date.issued2021
dc.description.abstract© 2021 Institute of Physics Publishing. All rights reserved.The aim of this work was to study the effect of the reduced acquisition time of PET 11C-MET examination on the quality of primary brain tumors differential diagnosis. 57 patients with histologically verified diagnoses were recruited (glioblastoma n=20, anaplastic astrocytoma n=11, diffuse astrocytoma n=11, oligodendroglioma n=9 and anaplastic oligodendroglioma n=6). The scan time was varied in the range of 2-20 min. Our study demonstrated that in the case of intravenous administration of 11C-MET simultaneously with the start of scanning, the quality of primary gliomas differential diagnosis does not depend on the scan time. Therefor it becomes possible increasing the number of patients and reducing the acquisition time. The T/N60 ratio (T/N ratio measured in the first 60 seconds after 11C-MET intravenous injection) is equally successful parameter for glioma differential diagnosis as the traditional T/N ratio.
dc.identifier.citationInfluence of 11C-MET PET acquisition time for differential diagnosis of human brain gliomas / Vikhrova, N. [et al.] // Journal of Physics: Conference Series. - 2021. - 2058. - № 1. - 10.1088/1742-6596/2058/1/012038
dc.identifier.doi10.1088/1742-6596/2058/1/012038
dc.identifier.urihttps://www.doi.org/10.1088/1742-6596/2058/1/012038
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85119497010&origin=resultslist
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/24990
dc.relation.ispartofJournal of Physics: Conference Series
dc.titleInfluence of 11C-MET PET acquisition time for differential diagnosis of human brain gliomas
dc.typeConference Paper
dspace.entity.typePublication
oaire.citation.issue1
oaire.citation.volume2058
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