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RADIOSENSITIZATION EFFECT OF BISMUTH-BASED NANOSHEETS UNDER PROTON BEAM IRRADIATION

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dc.contributor.authorKolmanovich, D.
dc.contributor.authorPopov, A.
dc.contributor.authorZelepukin, I.
dc.contributor.authorShemyakov, A.
dc.contributor.authorSavintseva, I.
dc.contributor.authorKotelnikova, A.
dc.contributor.authorChukavin, N.
dc.contributor.authorPivovarov, N.
dc.contributor.authorDeyev, S.
dc.contributor.authorKabashin, A.
dc.contributor.authorZavestovskaya, I.
dc.contributor.authorЗавестовская, Ирина Николаевна
dc.date.accessioned2025-11-20T10:01:38Z
dc.date.available2025-11-20T10:01:38Z
dc.date.issued2024
dc.description.abstractRadiation therapy is used as the first line of therapy in more than 50% of patients with malignant tumors [1]. However, this therapeutic approach still has difficulties in effectively delivering the dose directly to the tumor growth zone. The transition to proton therapy of the tumor makes it possible to increase the accuracy of dose unloading, since the main proton energy is released in the biological tissue at the end of the particle trajectory ("Bragg peak") in accordance with the profile of the deep dose [2]. Despite the numerous known benefits of proton beam therapy, it has certain limitations of effectiveness due to the low therapeutic yield. One of the most promising methods of promoting proton therapy is associated with the use of nanotechnology approaches, which involve the use of nanoparticles as sensitizers for improved results caused by radiotherapy. Nanoparticles containing elements with high electron density (high Z element), such as bismuth, can act as such a radio sensitizer.
dc.identifier.citationRADIOSENSITIZATION EFFECT OF BISMUTH-BASED NANOSHEETS UNDER PROTON BEAM IRRADIATION / Kolmanovich D. [и др.] // Инновационные технологии ядерной медицины и лучевой диагностики. Инновационные ядерно-физические методы высокотехнологичной медицины: Сборник тезисов III Международной научной конференции и VI Международной молодежной школы. - 2024. - С. 65-66
dc.identifier.urihttps://openrepository.mephi.ru/handle/123456789/39799
dc.publisherНИЯУ МИФИ
dc.titleRADIOSENSITIZATION EFFECT OF BISMUTH-BASED NANOSHEETS UNDER PROTON BEAM IRRADIATION
dc.typeArticle
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscovery1a1d2a9c-068f-48c6-b18a-7da3ce75cf7a
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2024_Инновационные технологии ядерной медицины и лучевой диагностики и терапии