Publication:
You shall not pass: Ti nanospike-based sterilizer in fluid flow reactor

Дата
2021
Авторы
Saraeva, I. N.
Tolordava, E. R.
Sozaev, I. V.
Nastulyavichus, A. A.
Gonchukov, S. A.
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Научные группы
Организационные подразделения
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Институт лазерных и плазменных технологий
Стратегическая цель Института ЛаПлаз – стать ведущей научной школой и ядром развития инноваций по лазерным, плазменным, радиационным и ускорительным технологиям, с уникальными образовательными программами, востребованными на российском и мировом рынке образовательных услуг.
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Аннотация
We report the laser-ablative fabrication of antibacterial nanostructures, combining mechanical and chemotoxic effects, by femto- and nanosecond laser ablation and their testing on Staphylococcus aureus and Pseudomonas aeruginosa strains. A Ti surface, covered with nanospikes and periodical surface ripples, provides a strong anti-biofilm effect, and the addition of cytotoxic nanoparticles (NPs) (Ag, Se) enhances the overall bactericidal activities. A flow reactor, including Ti nanospike-covered wafers as a through-flow sterilizer, allowed reduction of the bacterial population by two orders. Several types of nanostructures with/without biofilms were characterized by scanning electron microscopy and energy-dispersive x-ray spectroscopy. Their antibacterial properties were demonstrated by standard live/dead tests and were suggested to originate from the combined chemical toxicity of NPs and mechanical damage caused by sharp nanoscale relief on Ti.
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Цитирование
You shall not pass: Ti nanospike-based sterilizer in fluid flow reactor / Saraeva, IN [et al.] // Laser Physics Letters. - 2021. - 18. - № 3. - 10.1088/1612-202X/abdece
URI
https://www.doi.org/10.1088/1612-202X/abdece
 https://www.scopus.com/record/display.uri?eid=2-s2.0-85102301966&origin=resultslist
 http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000619553800001
 https://openrepository.mephi.ru/handle/123456789/23714
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