Publication: The effects of electromagnetic field and γ-radiation on cell proliferation and regeneration in planarian Schmidtea mediterranea
Дата
2019
Авторы
Matchuk, O. N.
Sarapultseva, E. I.
Uskalova, D.
Markina, H.
Savina, N.
Zamulaeva, I. A.
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© Published under licence by IOP Publishing Ltd. We have shown that γ-irradiation at dose of 10 Gy and low-intensity electromagnetic fields (EMF, 900 MHz, 100 μW/cm 2 , 180 min) significantly compromised cell proliferation of planarian S. mediterranea regenerating after decapitation. Using flow cytometry we have shown that 24 hours after exposure to γ-rays and EMF the index of proliferation established as the total amount of cells at S and G2/M phases was 2.8 and 1.8 lower than that in controls respectively. Our data therefore provide the first experimental evidence for the effects of medium-dose γ-irradiation on regeneration in planaria which is attributed to radiation-induced compromised proliferation activity.
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The effects of electromagnetic field and γ-radiation on cell proliferation and regeneration in planarian Schmidtea mediterranea / Matchuk, O.N. [et al.] // IOP Conference Series: Materials Science and Engineering. - 2019. - 487. - № 1. - 10.1088/1757-899X/487/1/012018