Publication: Polycationic Photosensitizers as Effective Anticancer Agents That Destroy Cancer Stem Cells, Cancer Vascularization and Induce Protective Desmoplastic Reaction around Lung Cancers
Дата
2024
Авторы
Kogan, E.
Meerovich, G.
Karshieva, S.
Akhlyustina, E.
Loschenov, V.
Меерович, Геннадий Александрович
Journal Title
Journal ISSN
Volume Title
Издатель
Аннотация
PDT using PSs based on polycationic derivatives of synthetic bacteriochlorin against Lewis lung carcinoma provides effective inhibition of tumor growth with an increase in the lifespan and survival of mice in the group. PDT with polycationic photosensitizers destroys CSCs and tumor neovascularization, and activates the desmoplastic reaction. These results open up new opportunities for increasing the effectiveness of treatment and reducing the incidence of relapses and metastases after PDT.
Описание
Ключевые слова
Photosensitizers , Photochemical Properties , Tumor Imaging , Photodynamic Therapy , Photothermal Therapy
Цитирование
Polycationic Photosensitizers as Effective Anticancer Agents That Destroy Cancer Stem Cells, Cancer Vascularization and Induce Protective Desmoplastic Reaction around Lung Cancers / Kogan, E. [et al.] // Photonics. - 2024. - 11. - № 6. - 10.3390/photonics11060485