Publication: Intraoperative Creation of Tissue-Engineered Grafts with Minimally Manipulated Cells: New Concept of Bone Tissue Engineering In Situ
Дата
2022
Авторы
Krasilnikova, O. A.
Baranovskii, D. S.
Yakimova, A. O.
Arguchinskaya, N.
Kisel, A.
Klabukov, I. D.
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Аннотация
Transfer of regenerative approaches into clinical practice is limited by strict legal regulation of in vitro expanded cells and risks associated with substantial manipulations. Isolation of cells for the enrichment of bone grafts directly in the Operating Room appears to be a promising solution for the translation of biomedical technologies into clinical practice. These intraoperative approaches could be generally characterized as a joint concept of tissue engineering in situ. Our review covers techniques of intraoperative cell isolation and seeding for the creation of tissue-engineered grafts in situ, that is, directly in the Operating Room. Up-to-date, the clinical use of tissue-engineered grafts created in vitro remains a highly inaccessible option. Fortunately, intraoperative tissue engineering in situ is already available for patients who need advanced treatment modalities.
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Цитирование
Intraoperative Creation of Tissue-Engineered Grafts with Minimally Manipulated Cells: New Concept of Bone Tissue Engineering In Situ / Krasilnikova, O. A. [et al.] // Bioengineering. - 2022. - 9. - № 11. - 10.3390/bioengineering9110704
URI
https://www.doi.org/10.3390/bioengineering9110704
https://www.scopus.com/record/display.uri?eid=2-s2.0-85147166980&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000894353600001
https://openrepository.mephi.ru/handle/123456789/28324
https://www.scopus.com/record/display.uri?eid=2-s2.0-85147166980&origin=resultslist
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=WOS_CPL&DestLinkType=FullRecord&UT=WOS:000894353600001
https://openrepository.mephi.ru/handle/123456789/28324