Publication: Optical Label-Free Method for Characterization of Kinetics of Antibodies to SARS-CoV-2
Дата
2022
Авторы
Bragina, V. A.
Pushkarev, A. V.
Orlov, A. V.
Znoyko, S. L.
Novichikhin, D. O.
Guteneva, N. V.
Skirda, A. M.
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Аннотация
To date, a dangerous infectious disease of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-Co V-2) has been a significant source of morbidity and high mortality worldwide. In this work, an optical label-free method is developed for measurements and characterization of kinetics of antibodies to SARS-CoV-2 in real time. A biomarker of COVID-19, namely, spike protein of SARS-CoV-2 antigen was used as a model antigen. The proposed method employs inexpensive and widely available consumables compatible with various chemical interfaces. It is promising for assessment the kinetics of humoral response to SARS-CoV-2 infection or postvaccination. © 2022 IEEE.
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Optical Label-Free Method for Characterization of Kinetics of Antibodies to SARS-CoV-2 / Bragina, V.A. [et al.] // 2022 International Conference Laser Optics, ICLO 2022 - Proceedingss. - 2022. - 10.1109/ICLO54117.2022.9839705